1,8-Cineole

Product Name:

1,8-Cineole

Synonyms:

1,8-Cineo;1,8-Epoxy-p-Menthanel;Eucalyptol 99%;Oil Eucalyptus 80-85%;1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane 1,8-Cineole 1,8-Epoxy-p-menthane Cineole;Eucalyptol (cineole);1,8-CINEOL;1,8-CINEOLE

CAS:

470-82-6

MF:

C10H18O

MW:

154.25

EINECS:

207-431-5

Product Categories:

Inhibitors;Miscellaneous Natural Products;Heterocycles;Heterocyclic Compounds;Bicyclic Monoterpenes;Biochemistry;Intermediates & Fine Chemicals;Isotope Labeled Compounds;Pharmaceuticals;Isotope Labelled Compounds;Terpenes

Mol File:

470-82-6.mol

Melting point 

1-2 °C(lit.)

Boiling point 

176-177 °C(lit.)

density 

0.9225

FEMA 

2465 | EUCALYPTOL

refractive index 

n20/D 1.457(lit.)

Fp 

122 °F

storage temp. 

2-8°C

solubility 

3.5g/l

form 

Liquid

color 

Clear colorless to slightly yellow

Water Solubility 

Soluble in water(3500 mg/L (at 21°C). Miscible with ether, alcohol, chloroform, glacial acetic acid, oils. Soluble in ethanol, ethyl ether; slightly soluble in carbon tetrachloride.

JECFA Number

1234

Merck 

14,3895

BRN 

105109

Stability:

Stable. Flammable. Incompatible with acids, bases, strong oxidizing agents.

InChIKey

WEEGYLXZBRQIMU-WAAGHKOSSA-N

CAS DataBase Reference

470-82-6(CAS DataBase Reference)

NIST Chemistry Reference

Eucalyptol(470-82-6)

EPA Substance Registry System

Eucalyptol (470-82-6)

Hazard Codes 

Xi,F

Risk Statements 

10-37/38-41-36/37/38

Safety Statements 

26-39-16

RIDADR 

UN 1993 3/PG 3

WGK Germany 

2

RTECS 

OS9275000

TSCA 

Yes

HS Code 

2932 99 00

HazardClass 

3

PackingGroup 

III

Hazardous Substances Data

470-82-6(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: 2480 mg/kg

Chemical Properties

Colorless Liquid

Occurrence

Its name is derived from its presence in the essential oils of Eucalyptus globulus and Melaleuca leucadendron L. (essential oil of cajeput). It was originally identified in the essential oil of Artemisia maritime and subsequently in a large number (approx. 270) of other essential oils: rosemary, laurel leaves, clary sage, myrrh, cardamom, star anise, camphor, lavender, peppermint, Litsea guatemalensis, Luvunga scadens Roxb., Achillea micrantha and Salvia triloba. The essential oil of Eucalyptus polibrac tea has been reported to contain up to 91% eucalyptol. Also reported found in citrus oils and juices, guava, papaya, cinnamon bark, root and leaf, ginger, corn mint oil, spearmint, nutmeg, pepper, Thymus zygis, cardamom, cranberry, laurel, pepper, sweet marjoram, coriander, Spanish origanum, Ocimum basilicum, curcuma, sage, laurel, sweet and bitter fennel, myrtle leaf and berry, pimento and calamus.

Uses

eucalyptol is considered an antiseptic. This is a monoterpene compound that provides the fragrance associated with the essential oil of eucalyptus. eucalyptol is also used to fragrance cosmetic preparations.