Natural Salicylic Acid

Product Name:

Natural salicylic acid

Synonyms:

Salicylic acid, AR,99.5%;salicylic acid medical grade;Methisosildenafil Impurity 1;Technical salicylic acid;acidoo-idrossibenzoico;acidosalicilico;Advanced pain relief callus removers;Advanced pain relief corn removers

CAS:

69-72-7

MF:

C7H6O3

MW:

138.12

EINECS:

200-712-3

Mol File:

69-72-7.mol

Melting point 

158-161 °C(lit.)

Boiling point 

211 °C(lit.)

density 

1.44

vapor density 

4.8 (vs air)

vapor pressure 

1 mm Hg ( 114 °C)

refractive index 

1,565

FEMA 

3985 | 2-HYDROXYBENZOIC ACID

Fp 

157 °C

storage temp. 

Store at RT.

solubility 

ethanol: 1 M at 20 °C, clear, colorless

form 

Solid

pka

2.98(at 25℃)

color 

White to off-white

PH

2.4 (H2O)(saturated solution)

PH Range

Non0 uorescence (2.5) to dark blue 0 uorescence (4.0)

Water Solubility 

1.8 g/L (20 ºC)

λmax

210nm, 234nm, 303nm

Sensitive 

Light Sensitive

Sublimation 

70 ºC

Merck 

14,8332

JECFA Number

958

BRN 

774890

Stability:

Stable. Substances to be avoided include oxidizing agents, strong bases, iodine, fluorine. Combustible. Sensitive to light.

Major Application

Semiconductors, nanoparticles, photoresists, lubricating oils, UV absorbers, adhesive, leather, cleaner, hair dye, soaps, cosmetics, pain medication, analgesics, antibacterial agent, treatment of dandruff, hyperpigmented skin, tinea pedis, onychomycosis, osteoporosis, beriberi, fungicidal skin disease, autoimmune disease

InChIKey

YGSDEFSMJLZEOE-UHFFFAOYSA-N

CAS DataBase Reference

69-72-7(CAS DataBase Reference)

NIST Chemistry Reference

Benzoic acid, 2-hydroxy-(69-72-7)

EPA Substance Registry System

Salicylic acid (69-72-7)

Hazard Codes 

Xn,F

Risk Statements 

22-41-36/37/38-36-20/21/22-11

Safety Statements 

26-39-37/39-36-36/37-16

RIDADR 

UN 1648 3 / PGII

WGK Germany 

1

RTECS 

VO0525000

Autoignition Temperature

500 °C

TSCA 

Yes

HS Code 

29182100

Hazardous Substances Data

69-72-7(Hazardous Substances Data)

Toxicity

LD50 i.v. in mice: 500 mg/kg (Sota)

Occurrence

Unripe fruits and vegetables are natural sources of salicylic acid, particularly blackberries, blueberries, cantaloupes, dates, raisins, kiwi fruits, guavas, apricots, green pepper, olives, tomatoes, radish and chicory; also mushrooms. Some herbs and spices contain quite high amounts, although meat, poultry, fish, eggs and dairy products all have little to no salicylates. Of the legumes, seeds, nuts, and cereals, only almonds, water chestnuts and peanuts have significant amounts.

Uses

Salicylic acid is known for its ability to ease aches and pains and reduce fevers. These medicinal properties, particularly fever relief, have been known since ancient times, and it is used as an antiinflammatory drug.
In modern medicine, salicylic acid and its derivatives are used as constituents of some rubefacient products. For example, methyl salicylate is used as a liniment to soothe joint and muscle pain, and choline salicylate is used topically to relieve the pain of mouth ulcers. As with other beta hydroxy acids, salicylic acid is a key ingredient in many skin-care products for the treatment of seborrhoeic dermatitis, acne, psoriasis, calluses, corns, keratosis pilaris, and warts.

Uses

non-steroidal anti-inflammatory drugs

Definition

A crystalline aromatic carboxylic acid. It is used in medicines, as an antiseptic, and in the manufacture of azo dyes. Its ethanoyl (acetyl) ester is aspirin. See aspirin; methyl salicylate.

General Description

Odorless white to light tan solid. Sinks and mixes slowly with water.