Raspberry Ketone

Product Name:

Raspberry Ketone

Synonyms:

Dobutamine EP Impurity B;4-p-Hydroxylphenyl)-2-butone;Oxyphenalon;Rheosmin;Raspberry keton;RASPBERRY KETONE;RASBERRY KETONE;OXYPHENONE

CAS:

5471-51-2

MF:

C10H12O2

MW:

164.2

EINECS:

226-806-4

Product Categories:

Aromatics;Herb extract;Food and Feed Additive;Aromatic Ketones (substituted)

Mol File:

5471-51-2.mol

Melting point 

81-85 °C(lit.)

Boiling point 

200°C

density 

1.0326 (rough estimate)

FEMA 

2588 | 4-(P-HYDROXYPHENYL)-2-BUTANONE

refractive index 

1.5250 (estimate)

storage temp. 

Refrigerator

solubility 

95% ethanol: soluble50mg/mL, clear to slightly hazy, colorless to faint yellow or tan

pka

9.99±0.15(Predicted)

form 

Liquid

color 

Clear colorless

Water Solubility 

Insoluble in water.

JECFA Number

728

BRN 

776080

InChIKey

NJGBTKGETPDVIK-UHFFFAOYSA-N

CAS DataBase Reference

5471-51-2(CAS DataBase Reference)

NIST Chemistry Reference

2-Butanone, 4-(4-hydroxyphenyl)-(5471-51-2)

EPA Substance Registry System

2-Butanone, 4-(4-hydroxyphenyl)- (5471-51-2)

Hazard Codes 

Xn,Xi

Risk Statements 

22

Safety Statements 

26-36/37/39-36

WGK Germany 

2

RTECS 

EL8925000

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29145011

Chemical properties

It appears as white needle crystal or granular solid, exhibiting raspberry aroma and fruit aroma. The melting point temperature is 82~83 °C. It is insoluble in water and oil, being soluble in alcohol, ether and volatile oil.
The natural products exist in raspberry (raspberry) and so on.

Uses

1. Raspberry Ketone is used in the preparation of food spices with sweetening effect, can also be used for cosmetics and soap flavor. 
2. Raspberry Ketone is widely used in strawberry, raspberry, pineapple, peaches and other food flavors, usually used as a fixing agent in the fruity flavor. In daily flavor, it can be used in formulations such as jasmine, gardenia flowers and tuberose. As a modifier, it can be used in jasmine, gardenia, tuberose and other fragrant daily flavor. In food flavors, it is mostly used for strawberries, pineapple, peaches, plums, mayberry and other fragrance. In medicine, it is mostly used as intermediates.

Description

4-(p-Hydroxyphenyl)-2-butanone has a sweet, fruity, raspberry preserves odor. May be prepared by catalytic hydrogenation of phydroxy-benzylidene acetone in the presence of platinum black in ether or methanol or in the presence of palladium absorbed on charcoal.

Chemical Properties

4-(p-Hydroxyphenyl)-2-butanone has a sweet, fruity, raspberry preserves–type odor.

Chemical Properties

4-(4-Hydroxyphenyl)-2-butanone is a highly characteristic component of raspberry aroma. It forms colorless crystals (mp 82–83°C) with a sweet, fruity odor strongly reminiscent of raspberries. Raspberry ketone is prepared by alkali-catalyzed condensation of the alkali salt of 4-hydroxybenzaldehyde and acetone, followed by selective hydrogenation of the double bond in the resulting 4-hydroxybenzalacetone. Other syntheses start from phenol, which is converted into 4-(4-hydroxyphenyl)-2-butanone with methyl vinyl ketone or with 4-hydroxy-2-butanone.

Chemical Properties

white to slightly yellow powder or needles

Uses

The primary aroma compound of red raspberries, used in perfume compositions, shampoos, cosmetics and as a food additive. Also an impurity in the synthesis of Dobutamine (D494445).

Uses

Intermediates of Liquid Crystals

Definition

ChEBI: A ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at position 4 by a hydroxy group. It is found in a variety of fruits including raspberries, blackberries and cranberries, and is used in perfumery and cosmetics.

Taste threshold values

Taste characteristics at 40 ppm: fruity, jamy, berry, raspberry, and blueberry with seedy, cotton candy nuances

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. Flammable liquid. When heated to decomposition it emits acrid smoke and irritating fumes. See also KETONES.

Raw materials

Etanol-->Acetone-->p-Hydroxybenzaldehyde-->Methyl vinyl ketone-->4-Phenyl-1-butene-->4,4'-Carbonyldiphthalic acid