Terpineol

Product Name:

Terpineol

Synonyms:

TERPINEOL;TERPINEOL 101 (ALPHA);TERPINEOL 200 (ALPHA);TERPINEOL 318 TYPE;TERPINEOL 350;TERPINEOL, A-;TERPINEOL-ALPHA;Terpineol - Mixed Isomers

CAS:

8000-41-7

MF:

C10H18O

MW:

154.25

EINECS:

232-268-1

Product Categories:

Citrus aurantium (Seville orange);Curcuma longa (Turmeric);Elettaria Cardamomum (Cardamom);Nutrition Research;Organic Building Blocks;Panax ginseng;Alkenes;Cyclic;Organic Building Blocks;Alphabetical Listings;Certified Natural ProductsFlavors and Fragrances;Phytochemicals by Plant (Food/Spice/Herb);Sambucus nigra (Elderberry);Zingiber officinale (Ginger);Essential OilsFlavors and Fragrances;Flavors and Fragrances;Q-Z;Artemisia vulgaris;Aspalathus linearis (Rooibos tea);Boswellia carterii;Building Blocks;Chemical Synthesis

Mol File:

8000-41-7.mol

Melting point 

18°C

Boiling point 

214-224°C

density 

0.937

vapor pressure 

3 hPa (20 °C)

refractive index 

1.481-1.486

Fp 

95°C

storage temp. 

Store below +30°C.

solubility 

ethanol: soluble1.25ml/10ml, clear to slightly hazy, colorless to light yellow (50% ethanol)

form 

Liquid

color 

Clear colorless to slightly yellow

Water Solubility 

slightly

FreezingPoint 

2℃

Stability:

Stable. Combustible. Incompatible with strong oxidizing agents, strong acids.

InChIKey

WUOACPNHFRMFPN-UHFFFAOYSA-N

CAS DataBase Reference

8000-41-7(CAS DataBase Reference)

EPA Substance Registry System

Terpineol (8000-41-7)

Hazard Codes 

Xi

Risk Statements 

38-36/37/38-36/38-37/38

Safety Statements 

37-36-26-24/25

WGK Germany 

2

RTECS 

WZ6600000

TSCA 

Yes

HS Code 

29061990

Toxicity

LD50 orally in Rabbit: 4300 mg/kg

Spices

Terpineol naturally occurs in pine oil, lavender oil, gallo oil, orange leaf oil, neroli oil and other essential oils. Turpentine is a kind of fragrance obtained through the hydration of α-pinene olefin or β-pinene to generate hydrated terpene glycol, followed by dehydration and fractionation. Terpineol is one of the earliest synthetic fragrances to achieve industrial production. It is mainly used as soap essence, and it has been more than 100 years old. Terpineol is a bulk spice products with a world annual output of thousands of tons. It is used in a wide variety of cosmetic formulations, especially in the formulation of soaps and synthetic detergents, up to 30%. IFRA has no restrictions. 
Figure 1 shows the chemical reaction equation of the α-pinene terpineol.
Terpineol has the aroma of pine and lilac. It appears as a viscous liquid, but easy to subject to crystallization with the boiling point of 218 ~ 219 ℃, 85 ℃ / 400Pa, the melting point of 35 ℃ (α-terpineol). Mainly used to deploy lilac, lily of the valley, Acacia, orange blossom and other scented soap, cosmetics flavor. Pure α-terpineol can still be used for preparation of lemons, oranges, peaches and other food flavors. A lot of ester compounds prepared from terpineol are also excellent spices.

Toxicity

According to the data provided by RIFM, acute toxicity data of terpineol: oral LD50 4.3g / kg (rat), skin test LD50> 3g / kg (rabbit).

Synthesis method

The weight ratio of turpentine and 30% sulfuric acid ingredients is 1: 1.7 with 10% Pergal as emulsifier. The reaction temperature is 28-30 ℃. The reaction was allowed to stand for 24 hours and then stratified. The resulting hydrated terpene glycol crystals floated on the acid water; after removal of the acid water, the remained crystal and oil layer in the reaction pot was washed with water by 3 times; use dilute alkali to wash to neutral pH; apply rejection centrifuge to obtain hydrated terpene glycol crystal. 
The weight ratio of hydrated terpene glycol and 0.2% sulfuric acid ingredients is 1: 2; stir and send direct steam and indirect steam to heat to boiling; the reaction takes about 3 to 5 hours and ended until the specific gravity reached d204 0.933. Apply stand stratification and discharge the lower acid. Turbid layer is neutralized by dilute alkaline; remove the alkaline; stand for clarification; the oil layer is subject to fractionation and fractionally collected according to the proportion of distillate fraction; the finished or semi-finished product has a output of terpineol being 55% to 60%.

Chemical Properties

It appears as colorless liquid or low-melting transparent crystal with a clove flavor. 1 part of terpineol can be dissolved in 2 parts (volume) of 70% ethanol solution, being slightly soluble in water and glycerol.

Uses

Solvent for hydrocarbon materials, mutual solvent for resins and cellulose esters and ethers, perfumes, soaps, disinfectant, antioxidant, flavoring agent.