WS-3

Product Name:

WS-3

CAS:

39711-79-0

MF:

C13H25NO

MW:

211.34

EINECS:

254-599-0

Product Categories:

Mol File:

39711-79-0.mol

Melting point 

87-102 °C

alpha 

D -49 to -54°

Boiling point 

351.04°C (rough estimate)

density 

0.9305 (rough estimate)

FEMA 

3455 | N-ETHYL-2-ISOPROPYL-5-METHYLCYCLOHEXANE CARBOXAMIDE

refractive index 

1.4410 (estimate)

storage temp. 

Store at RT

pka

16.27±0.60(Predicted)

Water Solubility 

insoluble

JECFA Number

1601

Merck 

14,3825

InChIKey

VUNOFAIHSALQQH-UHFFFAOYSA-N

CAS DataBase Reference

39711-79-0(CAS DataBase Reference)

EPA Substance Registry System

Cyclohexanecarboxamide, N-ethyl-5-methyl-2-(1-methylethyl)- (39711-79-0)

Hazard Codes 

Xi,Xn

Risk Statements 

36-41-22

Safety Statements 

39-26

WGK Germany 

2

HS Code 

29242990

Toxicity

LD50 in mice, rats (g/kg): 5.3, 2.9 orally (Parrish)

Chemical Properties

white crystalline powder

Chemical Properties

N-ethyl-p-menthane-3-carboxamide is an odorless white, crystalline solid. The compound has a strong and clear physiological cooling effect and is used mainly in oral care products.

Chemical Properties

Slight menthol-like cooling effect aroma

Uses

Physiological coolant in foods, beverages, toiletries, cosmetics and pharmaceuticals.

Aroma threshold values

Aroma characteristics at 1.0%. Virtually odorless

Taste threshold values

Taste characteristics at 10 to 100 ppm. Intense lingering cooling. The cooling sensation builds slow but steadily and grows to a lingering cooling mouthfeel with a slightly camphoraceous and minty character.

Trade name

Winsense WS-3 (Renessenz)

Biological Activity

Cooling agent that is an agonist at TRPM8 receptors (EC 50 = 3.7 μ M).